Tetrazin 25mg Tablet is used in the treatment of chorea (abnormal, jerky, or involuntary movements) associated with Huntington’s disease, an inherited condition in which the nerve cells in the brain become damaged.
🛒 How to order this item?
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Show More
Tetrazin 25mg Tablet contains Tetrabenazine, which belongs to the group of medicines called Vesicular monoamine transporter 2 inhibitors. It is primarily used to treat hyperkinetic motor disorders associated with Huntington's chorea, an inherited neurodegenerative disease characterized by jerky, irregular, and uncontrollable movements.
It's important to note that Tetrazin 25mg Tablet is contraindicated in patients allergic to Tetrabenazine. Additionally, it should not be used in individuals with Parkinson-like symptoms, depression, active suicidal thoughts, pheochromocytoma (tumor of the adrenal gland), or kidney disorders.
Before starting treatment with Tetrazin 25mg Tablet, inform your doctor if you have any intolerance to certain sugars (such as lactose), heart problems like long QT syndrome heart rhythm disorders, or liver problems ranging from mild to severe hepatic disorders.
Caution should be exercised when using Tetrazin 25mg Tablet during pregnancy or in women planning for pregnancy, only if deemed necessary by the physician. However, it is not recommended for use in breastfeeding women.
This medication is not suitable for use in children and adolescents below 18 years of age. For elderly patients aged 65 years and above, Tetrazin 25mg Tablet should be used with caution after consulting a doctor.
Avoid alcohol consumption while taking Tetrazin 25mg Tablet, as it may increase drowsiness.
Use Tetrazin 25mg Tablet during pregnancy only if necessary, after consulting your doctor.
Avoid using Tetrazin 25mg Tablet while breastfeeding. Consult your doctor for advice.
Do not drive or operate machinery if you feel drowsy after taking Tetrazin 25mg Tablet.
Consult your doctor before using Tetrazin 25mg Tablet if you have kidney disorders.
Tetrazin 25mg Tablet with caution if you have liver problems. Consult your doctor before use.
Huntington's disease
Tetrazin 25mg Tablet works by reducing the level of certain chemicals that cause abnormal movements.
Depression and suicidality are two major adverse responses. Akathisia, restlessness, and agitation are all symptoms of Akathisia. Dysphagia, Parkinsonism Somnolence, and sedation
If an overdose occurs, seek medical attention immediately. Symptoms may include muscle spasms, uncontrolled eye movements, nausea, vomiting, dizziness, confusion, hallucinations, and tremors.
Movement disorders, Moderate to severe tardive dyskinesia
Tetrabenazine acts as a reversible inhibitor of human vesicular monoamine transporter type 2 (VMAT2). It primarily functions in the basal ganglia to deplete reserves of monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine. By lowering synaptic vesicle uptake, tetrabenazine effectively reduces the transmission of dopamine, which is essential for fine motor movement. This mechanism makes it effective for treating hyperkinetic movement disorders associated with conditions like Huntington's disease.
It's worth noting that tetrabenazine exhibits a low affinity for the dopamine D2 receptor in vitro, indicating that its therapeutic effects are primarily mediated through VMAT2 inhibition rather than direct interaction with dopamine receptors.
For the treatment of chorea associated with Huntington's disease in adults, the recommended oral dosage of tetrabenazine should be individualized and titrated slowly over several weeks to identify a dose that effectively reduces chorea and is well tolerated. The total daily dose can be up to 50 mg/day.
Here are the dosing recommendations:
Inform your doctor about all medications you are taking, including:
Do not take Tetrazin 25mg Tablet if you are allergic to Tetrabenazine or any other ingredients in the medication.
The pregnancy classification for tetrabenazine is Category C, indicating that there are no sufficient and well-controlled trials in pregnant women. Therefore, tetrabenazine should only be used during pregnancy if the potential benefits to the mother outweigh the potential risks to the fetus.
Regarding breastfeeding, tetrabenazine or its metabolites are not known to be excreted in human milk by nursing mothers. However, it's essential to consider that many medications can pass into breast milk and potentially cause adverse reactions in nursing infants. Therefore, a decision should be made whether to discontinue breastfeeding or discontinue tetrabenazine, taking into account the importance of the medication to the mother's health and the potential risks to the infant. This decision should be made in consultation with a healthcare professional.
Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.